Ambient Ionization Mass Spectrometry for Cancer Diagnosis and Surgical Margin Evaluation
نویسندگان
چکیده
منابع مشابه
Ambient Ionization Mass Spectrometry for Cancer Diagnosis and Surgical Margin Evaluation.
BACKGROUND There is a clinical need for new technologies that would enable rapid disease diagnosis based on diagnostic molecular signatures. Ambient ionization mass spectrometry has revolutionized the means by which molecular information can be obtained from tissue samples in real time and with minimal sample pretreatment. New developments in ambient ionization techniques applied to clinical re...
متن کاملMolecular diagnosis of cancer using ambient ionization mass spectrometry
Kerian, Kevin S. Ph.D., Purdue University, May 2015. Molecular Diagnosis of Cancer using Ambient Ionization Mass Spectrometry. Major Professor: R. Graham Cooks. My dissertation focuses on advancing the development and application of ambient ionization mass spectrometry methodology and technology to the biomedical field. The primary ambient ionization method used in my studies is desorption elec...
متن کاملNanotip Ambient Ionization Mass Spectrometry.
A method called nanotip ambient ionization mass spectrometry (NAIMS) is described, which applies high voltage between a tungsten nanotip and a metal plate to generate a plasma in which ionized analytes on the surface of the metal plate are directed to the inlet and analyzed by a mass spectrometer. The dependence of signal intensity is investigated as a function of the tip-to-plate distance, the...
متن کاملForensic applications of ambient ionization mass spectrometry.
This review highlights and critically assesses forensic applications in the developing field of ambient ionization mass spectrometry. Ambient ionization methods permit the ionization of samples outside the mass spectrometer in the ordinary atmosphere, with minimal sample preparation. Several ambient ionization methods have been created since 2004 and they utilize different mechanisms to create ...
متن کاملAmbient ionization mass spectrometry: a tutorial.
Ambient ionization is a set of mass spectrometric ionization techniques performed under ambient conditions that allows the direct analysis of sample surfaces with little or no sample pretreatment. Using combinations of different types of sample introduction systems and ionization methods, several novel techniques have been developed over the last few years with many applications (e.g., food saf...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2016
ISSN: 0009-9147,1530-8561
DOI: 10.1373/clinchem.2014.237172